Two Sets of Paralogous Genes Encode the Enzymes Involved in the Early Stages of Clavulanic Acid and Clavam Metabolite Biosynthesis in Streptomyces clavuligerus

Recently, a second copy of a gene encoding proclavaminate amidinohydrolase (pah1), an enzyme involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus, was identified and isolated. Using Southern analysis, we have now isolated second copies of th...

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Argitaratua izan da:	Antimicrob Agents Chemother
Egile Nagusiak:	Tahlan, Kapil, Park, Hyeon Ung, Wong, Annie, Beatty, Perrin H., Jensen, Susan E.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology (ASM) 2004
Gaiak:	Chemistry; Biosynthesis
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.930-939.2004
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