Two Sets of Paralogous Genes Encode the Enzymes Involved in the Early Stages of Clavulanic Acid and Clavam Metabolite Biosynthesis in Streptomyces clavuligerus

Recently, a second copy of a gene encoding proclavaminate amidinohydrolase (pah1), an enzyme involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus, was identified and isolated. Using Southern analysis, we have now isolated second copies of th...

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izdano v:	Antimicrob Agents Chemother
Principais autores:	Tahlan, Kapil, Park, Hyeon Ung, Wong, Annie, Beatty, Perrin H., Jensen, Susan E.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2004
Teme:	Chemistry; Biosynthesis
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353097/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982786/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.930-939.2004
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