Two Sets of Paralogous Genes Encode the Enzymes Involved in the Early Stages of Clavulanic Acid and Clavam Metabolite Biosynthesis in Streptomyces clavuligerus

Recently, a second copy of a gene encoding proclavaminate amidinohydrolase (pah1), an enzyme involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus, was identified and isolated. Using Southern analysis, we have now isolated second copies of th...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Tahlan, Kapil, Park, Hyeon Ung, Wong, Annie, Beatty, Perrin H., Jensen, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2004
Assuntos:
Chemistry; Biosynthesis
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC353097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14982786/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.3.930-939.2004
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