Two Sets of Paralogous Genes Encode the Enzymes Involved in the Early Stages of Clavulanic Acid and Clavam Metabolite Biosynthesis in Streptomyces clavuligerus

Recently, a second copy of a gene encoding proclavaminate amidinohydrolase (pah1), an enzyme involved in the early stages of clavulanic acid and clavam metabolite biosynthesis in Streptomyces clavuligerus, was identified and isolated. Using Southern analysis, we have now isolated second copies of th...

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Bibliografiske detaljer
Main Authors: Tahlan, Kapil, Park, Hyeon Ung, Wong, Annie, Beatty, Perrin H., Jensen, Susan E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Chemistry; Biosynthesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC353097/
https://ncbi.nlm.nih.gov/pubmed/14982786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.3.930-939.2004
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