Possible Involvement of the Drug Transporters P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2 in Disposition of Azithromycin

P glycoprotein and multidrug resistance-associated protein 2 (Mrp2), ATP-dependent membrane transporters, exist in a variety of normal tissues and play important roles in the disposition of various drugs. The present study seeks to clarify the contribution of P glycoprotein and/or Mrp2 to the dispos...

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Autori principali: Sugie, Masami, Asakura, Emiko, Zhao, Ying Lan, Torita, Shoko, Nadai, Masayuki, Baba, Kenji, Kitaichi, Kiyoyuki, Takagi, Kenji, Takagi, Kenzo, Hasegawa, Takaaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Pharmacology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC353093/
https://ncbi.nlm.nih.gov/pubmed/14982769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.3.809-814.2004
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