Shiga-Like Toxin II Impairs Hepatobiliary Transport of Doxorubicin in Rats by Down-Regulation of Hepatic P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2

We investigated the effect of Shiga-like toxin II (SLT-II), derived from Escherichia coli O157:H7, on the hepatobiliary excretion of doxorubicin, a substrate for P glycoprotein and the multidrug resistance-associated protein Mrp2, and on the expression of P glycoprotein and Mrp2 in rats. Histopathol...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Hidemura, Kazuhiko, Zhao, Ying Lan, Ito, Katsuki, Nakao, Akimasa, Tatsumi, Yasuaki, Kanazawa, Hiroaki, Takagi, Kenzo, Ohta, Michio, Hasegawa, Takaaki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2003
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC153315/
https://ncbi.nlm.nih.gov/pubmed/12709333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.5.1636-1642.2003
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars