Involvement of the Drug Transporters P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2 in Telithromycin Transport

The present study aims to investigate the role of P glycoprotein and multidrug resistance-associated protein (Mrp2) in the transport of telithromycin, a newly developed ketolide antibiotic, in vitro and in vivo. The in vitro experiments revealed that the intracellular accumulation of telithromycin i...

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Detalhes bibliográficos
Main Authors: Yamaguchi, Shoji, Zhao, Ying Lan, Nadai, Masayuki, Yoshizumi, Hideo, Cen, Xiaobo, Torita, Shoko, Takagi, Kenji, Takagi, Kenzo, Hasegawa, Takaaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346787/
https://ncbi.nlm.nih.gov/pubmed/16377671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.80-87.2006
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