Effect of Endotoxin on P-Glycoprotein-Mediated Biliary and Renal Excretion of Rhodamine-123 in Rats

The effects of Klebsiella pneumoniae endotoxin on the biliary excretion and renal handling of rhodamine-123 were investigated in rats at different times after intraperitoneal injection (1 mg/kg of body weight). The typical substrates for P glycoprotein, i.e., cyclosporine, colchicine, and erythromyc...

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Detalhes bibliográficos
Main Authors: Ando, Hideyuki, Nishio, Yuki, Ito, Katsuki, Nakao, Akimasa, Wang, Li, Zhao, Ying Lan, Kitaichi, Kiyoyuki, Takagi, Kenzo, Hasegawa, Takaaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90854/
https://ncbi.nlm.nih.gov/pubmed/11709325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3462-3467.2001
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