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Granulocyte Colony-Stimulating Factor Enhances Endotoxin-Induced Decrease in Biliary Excretion of the Antibiotic Cefoperazone in Rats

We have recently reported that endotoxin (lipopolysaccharide [LPS]) derived from Klebsiella pneumoniae dramatically decreased the biliary excretion of the β-lactam antibiotic cefoperazone (CPZ), which is primarily excreted into the bile via the anion transport system, in rats. The present study was...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Nadai, Masayuki, Matsuda, Izumi, Wang, Li, Itoh, Akio, Naruhashi, Kazumasa, Nabeshima, Toshitaka, Asai, Masaki, Hasegawa, Takaaki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105768/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9736531/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.9.2178
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