A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing

Background. Next-generation sequencing of cancers has identified important therapeutic targets and biomarkers. The goal of this pilot study was to compare the genetic changes in a human papillomavirus- (HPV-)positive and an HPV-negative head and neck tumor. Methods. DNA was extracted from the blood...

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Autori principali: Nichols, Anthony C., Chan-Seng-Yue, Michelle, Yoo, John, Xu, Wei, Dhaliwal, Sandeep, Basmaji, John, Szeto, Christopher C. T., Dowthwaite, Samuel, Todorovic, Biljana, Starmans, Maud H. W., Lambin, Philippe, Palma, David A., Fung, Kevin, Franklin, Jason H., Wehrli, Bret, Kwan, Keith, Koropatnick, James, Mymryk, Joe S., Boutros, Paul, Barrett, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Scholarly Research Network 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530794/
https://ncbi.nlm.nih.gov/pubmed/23304554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/809370
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