Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy

Cancers progress when the immune system fails to identify and eliminate malignant cells. Recognition of this, combined with advances in tumor immunology, has allowed development of therapies that induce effective anti-tumor immune responses. For incompletely-understood reasons, effective responses t...

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Bibliografiske detaljer
Udgivet i:	Oncoimmunology
Main Authors:	Gameiro, Steven F., Ghasemi, Farhad, Barrett, John W., Koropatnick, James, Nichols, Anthony C., Mymryk, Joe S., Maleki Vareki, Saman
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2018
Fag:	Original Research
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6169583/ https://ncbi.nlm.nih.gov/pubmed/30288365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1498439
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Treatment-naïve HPV+ head and neck cancers display a T-cell-inflamed phenotype distinct from their HPV- counterparts that has implications for immunotherapy

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