A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing

Background. Next-generation sequencing of cancers has identified important therapeutic targets and biomarkers. The goal of this pilot study was to compare the genetic changes in a human papillomavirus- (HPV-)positive and an HPV-negative head and neck tumor. Methods. DNA was extracted from the blood...

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Detalhes bibliográficos
Main Authors: Nichols, Anthony C., Chan-Seng-Yue, Michelle, Yoo, John, Xu, Wei, Dhaliwal, Sandeep, Basmaji, John, Szeto, Christopher C. T., Dowthwaite, Samuel, Todorovic, Biljana, Starmans, Maud H. W., Lambin, Philippe, Palma, David A., Fung, Kevin, Franklin, Jason H., Wehrli, Bret, Kwan, Keith, Koropatnick, James, Mymryk, Joe S., Boutros, Paul, Barrett, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: International Scholarly Research Network 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530794/
https://ncbi.nlm.nih.gov/pubmed/23304554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/809370
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