A Case Report and Genetic Characterization of a Massive Acinic Cell Carcinoma of the Parotid with Delayed Distant Metastases

We describe the presentation, management, and clinical outcome of a massive acinic cell carcinoma of the parotid gland. The primary tumor and blood underwent exome sequencing which revealed deletions in CDKN2A as well as PPP1R13B, which induces p53. A damaging nonsynonymous mutation was noted in EP3...

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Main Authors: Nichols, Anthony C., Chan-Seng-Yue, Michelle, Yoo, John, Agrawal, Sumit K., Starmans, Maud H. W., Waggott, Daryl, Harding, Nicholas J., Dowthwaite, Samuel A., Palma, David A., Fung, Kevin, Wehrli, Bret, MacNeil, S. Danielle, Lambin, Philippe, Winquist, Eric, Koropatnick, James, Mymryk, Joe S., Boutros, Paul C., Barrett, John W.
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2013
主題:
Case Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638544/
https://ncbi.nlm.nih.gov/pubmed/23653877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/270362
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