Major Chromosomal Breakpoint Intervals in Breast Cancer Co-Localize with Differentially Methylated Regions

Solid tumors exhibit chromosomal rearrangements resulting in gain or loss of multiple chromosomal loci (copy number variation, or CNV), and translocations that occasionally result in the creation of novel chimeric genes. In the case of breast cancer, although most individual tumors each have unique...

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Bibliografiske detaljer
Main Authors: Eric Tang, Man-Hung, Varadan, Vinay, Kamalakaran, Sitharthan, Zhang, Michael Q., Dimitrova, Nevenka, Hicks, James
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2012
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530719/
https://ncbi.nlm.nih.gov/pubmed/23293768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00197
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