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Effective normalization for copy number variation detection from whole genome sequencing

BACKGROUND: Whole genome sequencing enables a high resolution view of the human genome and provides unique insights into genome structure at an unprecedented scale. There have been a number of tools to infer copy number variation in the genome. These tools, while validated, also include a number of...

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Autors principals: Janevski, Angel, Varadan, Vinay, Kamalakaran, Sitharthan, Banerjee, Nilanjana, Dimitrova, Nevenka
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481445/
https://ncbi.nlm.nih.gov/pubmed/23134596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-S6-S16
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