Major Chromosomal Breakpoint Intervals in Breast Cancer Co-Localize with Differentially Methylated Regions

Solid tumors exhibit chromosomal rearrangements resulting in gain or loss of multiple chromosomal loci (copy number variation, or CNV), and translocations that occasionally result in the creation of novel chimeric genes. In the case of breast cancer, although most individual tumors each have unique...

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Hlavní autoři: Eric Tang, Man-Hung, Varadan, Vinay, Kamalakaran, Sitharthan, Zhang, Michael Q., Dimitrova, Nevenka, Hicks, James
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2012
Témata:
Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530719/
https://ncbi.nlm.nih.gov/pubmed/23293768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00197
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