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Major Chromosomal Breakpoint Intervals in Breast Cancer Co-Localize with Differentially Methylated Regions

Solid tumors exhibit chromosomal rearrangements resulting in gain or loss of multiple chromosomal loci (copy number variation, or CNV), and translocations that occasionally result in the creation of novel chimeric genes. In the case of breast cancer, although most individual tumors each have unique...

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Detalhes bibliográficos
Main Authors: Eric Tang, Man-Hung, Varadan, Vinay, Kamalakaran, Sitharthan, Zhang, Michael Q., Dimitrova, Nevenka, Hicks, James
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3530719/
https://ncbi.nlm.nih.gov/pubmed/23293768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2012.00197
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