Herkinorin dilates cerebral vessels via kappa opioid receptor and cyclic adenosine monophosphate (cAMP) in a piglet model

Since herkinorin is the first non-opioid mu agonist derived from salvinorin A that has the ability to induce cerebral vascular dilatation, we hypothesized that herkinorin could have similar vascular dilatation effect via the mu and kappa opioid receptors and the cAMP pathway. The binding affinities...

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Hauptverfasser: Ji, Fang, Wang, Zhenhong, Ma, Nan, Riley, John, Armstead, William M., Liu, Renyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529796/
https://ncbi.nlm.nih.gov/pubmed/23103502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2012.10.024
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