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“cAMP Sponge”: A Buffer for Cyclic Adenosine 3′, 5′-Monophosphate

BACKGROUND: While intracellular buffers are widely used to study calcium signaling, no such tool exists for the other major second messenger, cyclic AMP (cAMP). METHODS/PRINCIPAL FINDINGS: Here we describe a genetically encoded buffer for cAMP based on the high-affinity cAMP-binding carboxy-terminus...

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Detalhes bibliográficos
Main Authors: Lefkimmiatis, Konstantinos, Moyer, Mary Pat, Curci, Silvana, Hofer, Aldebaran M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766031/
https://ncbi.nlm.nih.gov/pubmed/19888343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007649
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