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Salvinorin A Administration after Global Cerebral Hypoxia/Ischemia Preserves Cerebrovascular Autoregulation via Kappa Opioid Receptor in Piglets

BACKGROUND: Cerebral hypoxia/ischemia (HI) is not uncommon during the perinatal period. If occurring, it can result in severe neurologic disabilities that persist throughout life. Salvinorin A, a non-opioid Kappa opioid receptors (KOR) selective agonist, has the potential to address this devastating...

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Detalhes bibliográficos
Main Authors: Wang, Zhenhong, Ma, Nan, Riley, John, Armstead, William M., Liu, Renyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404042/
https://ncbi.nlm.nih.gov/pubmed/22911847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041724
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