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SLAT regulates CD8(+) T cell clonal expansion in a Cdc42 and NFAT1 dependent manner

Following antigenic stimulation, CD8(+) T cells undergo clonal expansion and differentiation into cytotoxic T lymphocytes (CTLs) that can mount a strong defense against intracellular pathogens and tumors. SWAP-70-like adapter of T cells (SLAT), also known as Def6, is a novel guanine nucleotide excha...

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Bibliografski detalji
Glavni autori: Feau, Sonia, Schoenberger, Stephen P., Altman, Amnon, Bécart, Stéphane
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529792/
https://ncbi.nlm.nih.gov/pubmed/23197258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201685
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