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SLAT regulates CD8(+) T cell clonal expansion in a Cdc42 and NFAT1 dependent manner
Following antigenic stimulation, CD8(+) T cells undergo clonal expansion and differentiation into cytotoxic T lymphocytes (CTLs) that can mount a strong defense against intracellular pathogens and tumors. SWAP-70-like adapter of T cells (SLAT), also known as Def6, is a novel guanine nucleotide excha...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529792/ https://ncbi.nlm.nih.gov/pubmed/23197258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1201685 |
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