Permeases of the Sap Transporter Are Required for Cathelicidin Resistance and Virulence of Haemophilus ducreyi in Humans

Background. Haemophilus ducreyi encounters several classes of antimicrobial peptides (APs) in vivo and utilizes the sensitive-to-antimicrobial-peptides (Sap) transporter as one mechanism of AP resistance. A mutant lacking the periplasmic solute–binding component, SapA, was somewhat more sensitive to...

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Autors principals: Rinker, Sherri D., Gu, Xiaoping, Fortney, Kate R., Zwickl, Beth W., Katz, Barry P., Janowicz, Diane M., Spinola, Stanley M., Bauer, Margaret E.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529601/
https://ncbi.nlm.nih.gov/pubmed/22930807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis525
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