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Permeases of the Sap Transporter Are Required for Cathelicidin Resistance and Virulence of Haemophilus ducreyi in Humans

Background. Haemophilus ducreyi encounters several classes of antimicrobial peptides (APs) in vivo and utilizes the sensitive-to-antimicrobial-peptides (Sap) transporter as one mechanism of AP resistance. A mutant lacking the periplasmic solute–binding component, SapA, was somewhat more sensitive to...

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Bibliografiske detaljer
Main Authors: Rinker, Sherri D., Gu, Xiaoping, Fortney, Kate R., Zwickl, Beth W., Katz, Barry P., Janowicz, Diane M., Spinola, Stanley M., Bauer, Margaret E.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529601/
https://ncbi.nlm.nih.gov/pubmed/22930807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis525
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