Permeases of the Sap Transporter Are Required for Cathelicidin Resistance and Virulence of Haemophilus ducreyi in Humans

Background. Haemophilus ducreyi encounters several classes of antimicrobial peptides (APs) in vivo and utilizes the sensitive-to-antimicrobial-peptides (Sap) transporter as one mechanism of AP resistance. A mutant lacking the periplasmic solute–binding component, SapA, was somewhat more sensitive to...

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Detalhes bibliográficos
Main Authors: Rinker, Sherri D., Gu, Xiaoping, Fortney, Kate R., Zwickl, Beth W., Katz, Barry P., Janowicz, Diane M., Spinola, Stanley M., Bauer, Margaret E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529601/
https://ncbi.nlm.nih.gov/pubmed/22930807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis525
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