Permeases of the Sap Transporter Are Required for Cathelicidin Resistance and Virulence of Haemophilus ducreyi in Humans

Background. Haemophilus ducreyi encounters several classes of antimicrobial peptides (APs) in vivo and utilizes the sensitive-to-antimicrobial-peptides (Sap) transporter as one mechanism of AP resistance. A mutant lacking the periplasmic solute–binding component, SapA, was somewhat more sensitive to...

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Bibliographic Details
Main Authors: Rinker, Sherri D., Gu, Xiaoping, Fortney, Kate R., Zwickl, Beth W., Katz, Barry P., Janowicz, Diane M., Spinola, Stanley M., Bauer, Margaret E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2012
Subjects:
Major Articles and Brief Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529601/
https://ncbi.nlm.nih.gov/pubmed/22930807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis525
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