TLR Signaling Prevents Hyperoxia-Induced Lung Injury by Protecting the Alveolar Epithelium from Oxidant-Mediated Death

Mechanical ventilation using high oxygen tensions is often necessary to treat patients with respiratory failure. Recently, TLRs were identified as regulators of noninfectious oxidative lung injury. IRAK-M is an inhibitor of MyD88-dependent TLR signaling. Exposure of mice deficient in IRAK-M (IRAK-M(...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Ballinger, Megan N., Newstead, Michael W., Zeng, Xianying, Bhan, Urvashi, Horowitz, Jeffrey C., Moore, Bethany B., Pinsky, David J., Flavell, Richard A., Standiford, Theodore J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529412/
https://ncbi.nlm.nih.gov/pubmed/22661086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103124
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi