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Epigenetic Regulation of Tolerance to Toll-Like Receptor Ligands in Alveolar Epithelial Cells

To protect the host against exuberant inflammation and injury responses, cells have the ability to become hyporesponsive or “tolerized” to repeated stimulation by microbial and nonmicrobial insults. The lung airspace is constantly exposed to a variety of exogenous and endogenous Toll-like receptor (...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Neagos, Jacqueline, Standiford, Theodore J., Newstead, Michael W., Zeng, Xianying, Huang, Steven K., Ballinger, Megan N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4742943/
https://ncbi.nlm.nih.gov/pubmed/25965198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0057OC
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