Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands

We have previously discovered a synergistically therapeutic combination of two Toll-like receptor ligands, an oligodeoxynucleotide (ODN) and Pam2CSK4. Aerosolization of these ligands stimulates innate immunity within the lungs to prevent pneumonia from bacterial and viral pathogens. Here we examined...

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Detalhes bibliográficos
Main Authors: Alfaro, Victoria Y., Goldblatt, David L., Valverde, Gabriella R., Munsell, Mark F., Quinton, Lee J., Walker, Adam K., Dantzer, Robert, Varadhachary, Atul, Scott, Brenton L., Evans, Scott E., Tuvim, Michael J., Dickey, Burton F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915096/
https://ncbi.nlm.nih.gov/pubmed/24567720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00008
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