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Safety, tolerability, and biomarkers of the treatment of mice with aerosolized Toll-like receptor ligands
We have previously discovered a synergistically therapeutic combination of two Toll-like receptor ligands, an oligodeoxynucleotide (ODN) and Pam2CSK4. Aerosolization of these ligands stimulates innate immunity within the lungs to prevent pneumonia from bacterial and viral pathogens. Here we examined...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915096/ https://ncbi.nlm.nih.gov/pubmed/24567720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00008 |
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