PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury

Fibrotic disorders of the lung are associated with perturbations in the plasminogen activation system. Specifically, plasminogen activator inhibitor-1 (PAI-1) expression is increased relative to the plasminogen activators. A direct role for this imbalance in modulating the severity of lung scarring...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Osterholzer, John J, Christensen, Paul J, Lama, Vibha, Horowitz, Jeffrey C, Hattori, Noboru, Subbotina, Natalya, Cunningham, Andrew, Lin, Yujing, Murdock, Benjamin J, Morey, Roger E, Olszewski, Michal A, Lawrence, Daniel A, Simon, Richard H, Sisson, Thomas H
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529409/
https://ncbi.nlm.nih.gov/pubmed/22262246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.3992
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados