IDIOPATHIC PULMONARY FIBROSIS: NEW CONCEPTS IN PATHOGENESIS AND IMPLICATIONS FOR DRUG THERAPY

Por Horowitz, Jeffrey C., Thannickal, Victor J.
Publicado em 2006

Evolving Concepts of Apoptosis in Idiopathic Pulmonary Fibrosis

Por Thannickal, Victor J., Horowitz, Jeffrey C.
Publicado em 2006

Epithelial–Mesenchymal Interactions in Pulmonary Fibrosis

Por Horowitz, Jeffrey C., Thannickal, Victor J.
Publicado em 2006

Stress in the ER (Endoplasmic Reticulum): A Matter of Life and Death for Epithelial Cells

Por Horowitz, Jeffrey C., Limper, Andrew H.
Publicado em 2008

Outstaying their Welcome: The Persistent Myofibroblast in IPF

Por Huang, Steven K., Horowitz, Jeffrey C.
Publicado em 2014

Mesenchymal Cell Fate and Phenotypes in the Pathogenesis of Emphysema

Por Horowitz, Jeffrey C., Martinez, Fernando J., Thannickal, Victor J.
Publicado em 2009

Activated alveolar epithelial cells initiate fibrosis through autocrine and paracrine secretion of connective tissue growth factor

Por Yang, Jibing, Velikoff, Miranda, Canalis, Ernesto, Horowitz, Jeffrey C., Kim, Kevin K.
Publicado em 2014

Plakoglobin expression in fibroblasts and its role in idiopathic pulmonary fibrosis

Por Matthes, Stephanie A., LaRouere, Thomas J., Horowitz, Jeffrey C., White, Eric S.
Publicado no BMC Pulm Med (2015)

Plasminogen Activation–Induced Pericellular Fibronectin Proteolysis Promotes Fibroblast Apoptosis

Por Horowitz, Jeffrey C., Rogers, David S., Simon, Richard H., Sisson, Thomas H., Thannickal, Victor J.
Publicado em 2008

Combinatorial activation of FAK and AKT by transforming growth factor-β1 confers an anoikis-resistant phenotype to myofibroblasts

Por Horowitz, Jeffrey C., Rogers, David S., Sharma, Vishal, Vittal, Ragini, White, Eric S., Cui, Zongbin, Thannickal, Victor J.
Publicado em 2006

Endothelin-1 and Transforming Growth Factor-β1 Independently Induce Fibroblast Resistance to Apoptosis via AKT Activation

Por Kulasekaran, Priya, Scavone, Casey A., Rogers, David S., Arenberg, Douglas A., Thannickal, Victor J., Horowitz, Jeffrey C.
Publicado em 2009

Intestinal Fibrosis is Reduced by Early Elimination of Inflammation in a Mouse Model of IBD

Por Johnson, Laura A., Luke, Amy, Sauder, Kay, Moons, David S., Horowitz, Jeffrey C., Higgins, Peter D.R.
Publicado em 2011

Ultrasound Strain Measurements for Evaluating Local Pulmonary Ventilation

Por Rubin, Jonathan M., Horowitz, Jeffrey C., Sisson, Thomas H., Kim, Kang, Ortiz, Luis A., Hamilton, James D.
Publicado no IEEE Int Ultrason Symp (2015)

Pulmonary Fibrosis Induced by γ-Herpesvirus in Aged Mice Is Associated With Increased Fibroblast Responsiveness to Transforming Growth Factor-β

Por Naik, Payal N., Horowitz, Jeffrey C., Moore, Thomas A., Wilke, Carol A., Toews, Galen B., Moore, Bethany B.
Publicado em 2012

The vitronectin RGD motif regulates TGF-β-induced alveolar epithelial cell apoptosis

Por Wheaton, Amanda K., Velikoff, Miranda, Agarwal, Manisha, Loo, Tiffany T., Horowitz, Jeffrey C., Sisson, Thomas H., Kim, Kevin K.
Publicado no Am J Physiol Lung Cell Mol Physiol (2016)

Matrix Stiffness Corresponding to Strictured Bowel Induces a Fibrogenic Response in Human Colonic Fibroblasts

Por Johnson, Laura A., Rodansky, Eva S., Sauder, Kay L., Horowitz, Jeffrey C., Mih, Justin D., Tschumperlin, Daniel J., Higgins, Peter D.
Publicado em 2013

Activation of the Pro-survival Phosphatidylinositol 3-Kinase/AKT Pathway by Transforming Growth Factor-β1 in Mesenchymal Cells Is Mediated by p38 MAPK-dependent Induction of an Aut...

Por Horowitz, Jeffrey C., Lee, Daniel Y., Waghray, Meghna, Keshamouni, Venkateshwar G., Thomas, Peedikayil E., Zhang, Hengmin, Cui, Zongbin, Thannickal, Victor J.
Publicado em 2003

Modulation of Prosurvival Signaling in Fibroblasts by a Protein Kinase Inhibitor Protects against Fibrotic Tissue Injury

Por Vittal, Ragini, Horowitz, Jeffrey C., Moore, Bethany B., Zhang, Hengmin, Martinez, Fernando J., Toews, Galen B., Standiford, Theodore J., Thannickal, Victor J.
Publicado em 2005

NADPH Oxidase-4 Mediates Myofibroblast Activation and Fibrogenic Responses to Lung Injury

Por Hecker, Louise, Vittal, Ragini, Jones, Tamara, Jagirdar, Rajesh, Luckhardt, Tracy R., Horowitz, Jeffrey C., Pennathur, Subramaniam, Martinez, Fernando J., Thannickal, Victor J.
Publicado em 2009

Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways

Por Huang, Steven K., White, Eric S., Wettlaufer, Scott H., Grifka, Heather, Hogaboam, Cory M., Thannickal, Victor J., Horowitz, Jeffrey C., Peters-Golden, Marc
Publicado em 2009