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NADPH Oxidase-4 Mediates Myofibroblast Activation and Fibrogenic Responses to Lung Injury

The NADPH oxidase (NOX) family of enzymes, which catalyze the reduction of O(2) to form reactive oxygen species (ROS), have increased in number during eukaryotic evolution1,2. Seven isoforms of the NOX gene family have been identified in mammals; however, specific roles of NOX enzymes in mammalian p...

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Detalhes bibliográficos
Main Authors: Hecker, Louise, Vittal, Ragini, Jones, Tamara, Jagirdar, Rajesh, Luckhardt, Tracy R., Horowitz, Jeffrey C., Pennathur, Subramaniam, Martinez, Fernando J., Thannickal, Victor J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743335/
https://ncbi.nlm.nih.gov/pubmed/19701206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2005
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