Efferocytosis of apoptotic alveolar epithelial cells is sufficient to initiate lung fibrosis

Type II alveolar epithelial cell (AEC) apoptosis is a prominent feature of fibrotic lung diseases and animal models of pulmonary fibrosis. While there is growing recognition of the importance of AEC injury and apoptosis as a causal factor in fibrosis, the underlying mechanisms that link these proces...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Kim, Kevin K., Dotson, Megan R., Agarwal, Manisha, Yang, Jibing, Bradley, Patrick B., Subbotina, Natalia, Osterholzer, John J., Sisson, Thomas H.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193049/
https://ncbi.nlm.nih.gov/pubmed/30333529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1074-z
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