Activated Alveolar Epithelial Cells Initiate Fibrosis through Secretion of Mesenchymal Proteins

Fibrosis is characterized by accumulation of activated fibroblasts and pathological deposition of fibrillar collagens. Activated fibroblasts overexpress matrix proteins and release factors that promote further recruitment of activated fibroblasts, leading to progressive fibrosis. The contribution of...

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Detalhes bibliográficos
Main Authors: Yang, Jibing, Wheeler, Sarah E., Velikoff, Miranda, Kleaveland, Kathryn R., LaFemina, Michael J., Frank, James A., Chapman, Harold A., Christensen, Paul J., Kim, Kevin K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814683/
https://ncbi.nlm.nih.gov/pubmed/24012677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.07.016
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