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Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

Mechanisms leading to fibroblast accumulation during pulmonary fibrogenesis remain unclear. Although there is in vitro evidence of lung alveolar epithelial-to-mesenchymal transition (EMT), whether EMT occurs within the lung is currently unknown. Biopsies from fibrotic human lungs demonstrate epithel...

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Autors principals: Kim, Kevin K., Kugler, Matthias C., Wolters, Paul J., Robillard, Liliane, Galvez, Michael G., Brumwell, Alexis N., Sheppard, Dean, Chapman, Harold A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1551904/
https://ncbi.nlm.nih.gov/pubmed/16924102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605669103
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