Inhibition of Epithelial-to-Mesenchymal Transition and Pulmonary Fibrosis by Methacycline

A high-throughput small-molecule screen was conducted to identify inhibitors of epithelial–mesenchymal transition (EMT) that could be used as tool compounds to test the importance of EMT signaling in vivo during fibrogenesis. Transforming growth factor (TGF)-β1–induced fibronectin expression and E-c...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Xi, Ying, Tan, Kevin, Brumwell, Alexis N., Chen, Steven C., Kim, Yong-Hyun, Kim, Thomas J., Wei, Ying, Chapman, Harold A.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2014
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930932/
https://ncbi.nlm.nih.gov/pubmed/23944988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0099OC
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