IGF-I 3′ Untranslated Region: Strain-Specific Polymorphisms and Motifs Regulating IGF-I in Osteoblasts

Reduced IGF-I is associated with low bone mass in humans and mice. C3H/He/J (C3H) mice have higher skeletal IGF-I and greater bone mass than C57BL/6J (B6). We hypothesized that strain-related genotypic differences in Igf1 affected skeletal function. The Igf1 coding region is nonpolymorphic, but its...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Smith, Spenser S., Kessler, Catherine B., Shenoy, Vikram, Rosen, Clifford J., Delany, Anne M.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2013
Sujets:
Growth Factors-Cytokines
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529377/
https://ncbi.nlm.nih.gov/pubmed/23183171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1476
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires