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Nocturnin Suppresses Igf1 Expression in Bone by Targeting the 3′ Untranslated Region of Igf1 mRNA

IGF-I is an anabolic factor that mediates GH and PTH actions in bone. Expression of skeletal Igf1 differs for inbred strains of mice, and Igf expression levels correlate directly with bone mass. Previously we reported that peroxisome proliferator-activated receptor-γ2 activation in bone marrow suppr...

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Bibliografski detalji
Glavni autori: Kawai, Masanobu, Delany, Anne M., Green, Carla B., Adamo, Martin L., Rosen, Clifford J.
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946149/
https://ncbi.nlm.nih.gov/pubmed/20685873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0407
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