Hypertension Susceptibility Loci and Blood Pressure Response to Antihypertensives – Results from the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) Study

BACKGROUND: To date, 39 SNPs have been associated with blood pressure (BP) or hypertension (HTN) in genome-wide association studies (GWAS) in Caucasians. Our hypothesis is that the loci/SNPs associated with BP/HTN are also associated with BP response to antihypertensive drugs. METHODS AND RESULTS: W...

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Huvudupphovsmän: Gong, Yan, McDonough, Caitrin W., Wang, Zhiying, Hou, Wei, Cooper-DeHoff, Rhonda M., Langaee, Taimour Y., Beitelshees, Amber L., Chapman, Arlene B., Gums, John G., Bailey, Kent R., Boerwinkle, Eric, Turner, Stephen T., Johnson, Julie A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529147/
https://ncbi.nlm.nih.gov/pubmed/23087401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.112.964080
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