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Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers–Danlos syndrome
Zinc is essential but potentially toxic, so intracellular zinc levels are tightly controlled. A key strategy used by many organisms to buffer cytosolic zinc is to store it within vesicles and organelles. It is yet unknown whether vesicular or organellar sites perform this function in mammals. Human...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529093/ https://ncbi.nlm.nih.gov/pubmed/23213233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211775110 |
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