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Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers–Danlos syndrome

Zinc is essential but potentially toxic, so intracellular zinc levels are tightly controlled. A key strategy used by many organisms to buffer cytosolic zinc is to store it within vesicles and organelles. It is yet unknown whether vesicular or organellar sites perform this function in mammals. Human...

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Bibliografische gegevens
Hoofdauteurs: Jeong, Jeeyon, Walker, Joel M., Wang, Fudi, Park, J. Genevieve, Palmer, Amy E., Giunta, Cecilia, Rohrbach, Marianne, Steinmann, Beat, Eide, David J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529093/
https://ncbi.nlm.nih.gov/pubmed/23213233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211775110
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