Transactivating function (AF) 2–mediated AF-1 activity of estrogen receptor α is crucial to maintain male reproductive tract function

Estrogen receptor alpha (ERα) is a ligand-dependent transcription factor containing two transcriptional activation function (AF) domains. AF-1 is in the N terminus of the receptor protein, and AF-2 activity is dependent on helix 12 of the C-terminal ligand-binding domain. We recently showed that two...

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Bibliografiset tiedot
Päätekijät: Arao, Yukitomo, Hamilton, Katherine J., Goulding, Eugenia H., Janardhan, Kyathanahalli S., Eddy, Edward M., Korach, Kenneth S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2012
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529064/
https://ncbi.nlm.nih.gov/pubmed/23213263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1216189110
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