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Ubiquitylation of p53 by the APC/C inhibitor Trim39
Tripartite motif 39 (Trim39) is a RING domain-containing E3 ubiquitin ligase able to inhibit the anaphase-promoting complex (APC/C) directly. Through analysis of Trim39 function in p53-positive and p53-negative cells, we have found, surprisingly, that p53-positive cells lacking Trim39 could not trav...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529062/ https://ncbi.nlm.nih.gov/pubmed/23213260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212047110 |
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