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Trim24 targets endogenous p53 for degradation
Numerous studies focus on the tumor suppressor p53 as a protector of genomic stability, mediator of cell cycle arrest and apoptosis, and target of mutation in 50% of all human cancers. The vast majority of information on p53, its protein-interaction partners and regulation, comes from studies of tum...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2710642/ https://ncbi.nlm.nih.gov/pubmed/19556538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813177106 |
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