CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice

The closely linked human protocadherin (Pcdh) α, β, and γ gene clusters encode 53 distinct protein isoforms, which are expressed in a combinatorial manner to generate enormous diversity on the surface of individual neurons. This diversity is a consequence of stochastic promoter choice and alternativ...

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Detaylı Bibliyografya
Asıl Yazarlar: Guo, Ya, Monahan, Kevin, Wu, Haiyang, Gertz, Jason, Varley, Katherine E., Li, Wei, Myers, Richard M., Maniatis, Tom, Wu, Qiang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2012
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3529044/
https://ncbi.nlm.nih.gov/pubmed/23204437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219280110
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