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CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice
The closely linked human protocadherin (Pcdh) α, β, and γ gene clusters encode 53 distinct protein isoforms, which are expressed in a combinatorial manner to generate enormous diversity on the surface of individual neurons. This diversity is a consequence of stochastic promoter choice and alternativ...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3529044/ https://ncbi.nlm.nih.gov/pubmed/23204437 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1219280110 |
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