Hematopoietic G-protein-coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor-knockout mice

Leukocyte chemotaxis is deemed instrumental in initiation and progression of atherosclerosis. It is mediated by G-protein-coupled receptors (e.g., CCR2 and CCR5), the activity of which is controlled by G-protein-coupled receptor kinases (GRKs). In this study, we analyzed the effect of hematopoietic...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Otten, Jeroen J. T., de Jager, Saskia C. A., Kavelaars, Annemieke, Seijkens, Tom, Bot, Ilze, Wijnands, Erwin, Beckers, Linda, Westra, Marijke M., Bot, Martine, Busch, Matthias, Bermudez, Beatriz, van Berkel, Theo J. C., Heijnen, Cobi J., Biessen, Erik A. L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Federation of American Societies for Experimental Biology 2013
Pynciau:
Research Communications
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3528319/
https://ncbi.nlm.nih.gov/pubmed/23047899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-205351
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