Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis

Growth differentiation factor (GDF) 15 is a member of the transforming growth factor β (TGF-β) superfamily, which operates in acute phase responses through a currently unknown receptor. Elevated GDF-15 serum levels were recently identified as a risk factor for acute coronary syndromes. We show that...

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Main Authors: de Jager, Saskia C.A., Bermúdez, Beatriz, Bot, Ilze, Koenen, Rory R., Bot, Martine, Kavelaars, Annemieke, de Waard, Vivian, Heijnen, Cobi J., Muriana, Francisco J.G., Weber, Christian, van Berkel, Theo J.C., Kuiper, Johan, Lee, Se-Jin, Abia, Rocio, Biessen, Erik A.L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039852/
https://ncbi.nlm.nih.gov/pubmed/21242297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100370
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