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Chemotherapy accelerates age-related development of tauopathy and results in loss of synaptic integrity and cognitive impairment

Cancer and its treatment are associated with neurotoxic side effects, including cognitive dysfunction, altered functional connectivity in the brain and structural abnormalities in white matter. There is evidence that cancer and its treatment can accelerate aging. Tau is a microtubule associated prot...

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Detalhes bibliográficos
Publicado no:Brain Behav Immun
Main Authors: Chiang, Angie C.A., Huo, Xiaojiao, Kavelaars, Annemieke, Heijnen, Cobi J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591052/
https://ncbi.nlm.nih.gov/pubmed/30953771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2019.04.005
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