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Pharmacological inhibition of HDAC6 reverses cognitive impairment and tau pathology as a result of cisplatin treatment

Chemotherapy-induced cognitive impairment (CICI) is a commonly reported neurotoxic side effect of chemotherapy, occurring in up to 75% cancer patients. CICI manifests as decrements in working memory, executive functioning, attention, and processing speed, and greatly interferes with patients’ daily...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Ma, Jiacheng, Huo, XiaoJiao, Jarpe, Matthew B., Kavelaars, Annemieke, Heijnen, Cobi J.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166273/
https://ncbi.nlm.nih.gov/pubmed/30270813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0604-3
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