Inhibition by Ethambutol of Mycolic Acid Transfer into the Cell Wall of Mycobacterium smegmatis

Ethambutol simultaneously inhibited the transfer (presumably via mycolyl acetyl trehalose) of mycolic acids into the cell wall and stimulated the synthesis of trehalose dimycolates of Mycobacterium smegmatis. Structural similarities of the drug and mycolyl acetyl trehalose suggested that competitive...

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Dades bibliogràfiques

Publicat a:	Antimicrob Agents Chemother
Autors principals:	Takayama, Kuni, Armstrong, Emma L., Kunugi, Keith A., Kilburn, James O.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1979
Matèries:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/485133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.2.240
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