Inhibition by Ethambutol of Mycolic Acid Transfer into the Cell Wall of Mycobacterium smegmatis

Ethambutol simultaneously inhibited the transfer (presumably via mycolyl acetyl trehalose) of mycolic acids into the cell wall and stimulated the synthesis of trehalose dimycolates of Mycobacterium smegmatis. Structural similarities of the drug and mycolyl acetyl trehalose suggested that competitive...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Takayama, Kuni, Armstrong, Emma L., Kunugi, Keith A., Kilburn, James O.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1979
Témata:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352831/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/485133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.16.2.240
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